Forty-three contributors examine theoretical components such as the impact of psychoneur immunology on stress, the impact of psychosocial stress on gene expression, the role of neurobiology and its effects on traumatization and resulting psychopathology, clinical models that aid in understanding the process of experiencing stressful life events and the subsequent accommodation of stress in our lives. Other topics include stress and physical illness, efforts of clinicians and researchers to develop an integrative model in understanding the spectrum of stress phenomena, and the role of factors such as personality variables.